Capillary Leak Index Versus Conventional Biomarkers in Predicting Sepsis-Related Outcomes

ConditionPeritonitis Infectious

Trial statusRecruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

Age18+

SponsorBenha University

About this trial

This study aims to evaluate the prognostic significance of CLI in predicting 28-day mortality and other outcomes in critically ill patients who develop post-operative abdominal sepsis.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

None

Disqualifiers

Pregnancy

Advanced liver disease (Child-Pugh class B or C) that might independently affect albumin levels

Advanced kidney disease (CKD stage 4 or 5) or patients on chronic dialysis

Expected mortality within 48 hours of ICU admission

Trial population

adult patients admitted to the ICU with post-operative secondary peritonitis requiring an ICU stay of at least 48 hours will be enrolled.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Capillary Leak Index Versus
Diagnostic test
Blood samples will be collected at three time points: within 1-2 hours of ICU admission (Day 0), Day 1, Day 2 and Day 7, to monitor trends in CLI and conventional biomarkers during the ICU stay. • CR

Treatment groups

100 Participants

are divided into 1 treatment group

Group A: adult patients admitted to the ICU with post-operative secondary peritonitis requiring an ICU stay o1 intervention

Trial outcomes

Primary outcomes

all-cause mortality

Time frame

From 1-10-2025 to 1-10-2026

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Benha University

Lead sponsor

Source ClinicalTrials.gov

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