Carbohydrate or Protein Drinks Before Exercise in the Heat
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-45
SponsorProvidence College
About this trial
This project examines whether consuming a high-protein or high-carbohydrate beverage before exercise in the heat impacts metabolism and heat balance during exercise, with the following research questions:
1. Does a high-protein vs. high-carbohydrate pre-exercise drink impact metabolism and body temperature responses during a treadmill walking in the heat? 2. Does a high-protein or high-carbohydrate drink change oxygen use and heat production during treadmill walking in the heat?
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Able to walk or run up to 5 mph on a treadmill
Able to consume products containing dairy (no allergy or dietary restrictions)
Disqualifiers
Following a diet that excludes any macronutrient group (low-carb or low-fat)
Diagnosed cardiovascular or metabolic diseases (hypertension, diabetes)
Diagnosed heat illness in past 3 months (heat exhaustion, heat stroke)
Trial design
Design model
Crossover
Treatments tested in this trial
Protein shake
Dietary supplement22 oz of a beverage containing 320 kilocalories (60g protein, 6g fat, 8g carbohydrate).
Carbohydrate shake
Dietary supplement22oz of a carbohydrate drink containing 320 kilocalories (75g carbohydrate, 3g protein, \<1g fat)
Treatment groups
16 Participants
are divided into 2 treatment groupsGroup A: High ProteinExperimental treatment 1 intervention
Group B: High CarbohydrateActive comparator 1 intervention
Trial outcomes
Primary outcomes
1
Metabolic Heat Production
Heat production measured during exercise at 6 watts/kg, calculated based on oxygen consumption and carbon dioxide production during exercise (indirect calorimetry)
Time frame
Measured during 60 minutes of steady state exercise in 36C, 40% humiditySecondary outcomes
1
Core Temperature
Internal temperature change during exercise
Time frame
Measured at rest and following 60 minutes of exercise in a warm (36C, 40% humidity) environment2
Urinary NGAL (ng/mL)
Measured after exercise in high-protein and high-carbohydrate trials, NGAL (neutrophil-gelatinase associated lipocalin; a marker of acute kidney injury) will be measured in urine samples in each trial to assess kidney function.
Time frame
Following 60 minutes of exercise in a warm environment (36C, 40% relative humidity)3
Urine Specific Gravity (USG)
Measured in urine samples provided before and after exercise, USG will be used as a marker of urine concentration and hydration status with each intervention.
Time frame
Measured before and after 60 minutes of exercise in a warm (36C, 40%RH) environment.4
Proteinuria
Measured after exercise in high-protein and high-carbohydrate trials, total protein content will be measured in urine samples in each trial to assess kidney function.
Time frame
Following 60 minutes of exercise in a warm environment (36C, 40% relative humidity)Locations
Sponsors and contacts
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Source ClinicalTrials.gov
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