The main hypothesis is that autonomic dysfunction cannot improve among patients reaching end-stage heart failure. To evaluate this, patients admitted with acute decompensated heart failure in Bispebjerg hospital, and history one or more admissions with the same condition within the prior year, will undergo repeated brief heart monitoring (10 min). Baseline recordings (at admission) will be compared with equivalent measurements before discharge to explore whether heart rate variability increases. Patients will be followed for six months after discharge from the hospital.
18-years age or older
admitted with acute decompensated heart failure for less than 48 h
pacemaker
not signed informed consent
other heart rhythm than sinus rhythm or atrial fibrillation
Patients admitted to the hospital with acute decompensated heart failure, regardless of measured left ventricle ejection fraction. Patients will be grouped according to rhythm: sinus rhythm and atrial fibrillation.
Cohort
Prospective
heart monitoring
Diagnostic testindividual comparison of heart rate variability at admission with a repeated measurement before discharge
number of rehospitalizations
number of emergency rehospitalizations, classified according to: 1. new decompensation of heart failure 2. side effects / complications to therapy for heart failure 3. other
Heart rate Variability change from admission to discharge
Measurement of heart-rate oscillations over a short term (30 min) of continuous three-lead electrocardiogram recording divided into two time domains: Domain 10min: relaxed, supine position for 10 min Domain 30 min: comprising the first 10 min-domain in addition to stand-up and walking for 5 min, followed by sitting relaxed until completing 30 min recording in total
Diastolic function
Measurement of changes diastolic function in right and left ventricle based on wavelet-ECG measurements
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