About this trial
Individuals aged 18-80 years who have been clinically diagnosed with multiple sclerosis and their caregivers will be included in the study.
Demographic data of the patients, including age, height, weight, and comorbidities, will be recorded. Disease-specific characteristics such as disease duration, presence of incontinence, ambulation status, and presence and severity of pain will be assessed. Functional status of the patients will be evaluated using the Expanded Disability Status Scale (EDSS) and the Multiple Sclerosis Impact Scale (MSIS). Symptoms related to depression and anxiety in patients will be assessed using the Hospital Anxiety and Depression Scale (HADS).
Subsequently, caregivers of the patients will be evaluated. The severity of insomnia will be assessed using the Insomnia Severity Index (ISI). Symptoms related to anxiety and depression will be evaluated using the Hospital Anxiety and Depression Scale (HADS). Caregiver burden will be assessed using the Zarit Caregiver Burden Scale.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age 18-80 years
Clinically diagnosed with multiple sclerosis by a neurologist
Being followed in the physical therapy and rehabilitation clinics during the study period
Having a primary or regular caregiver (family member)
Disqualifiers
Severe cognitive impairment or communication problems preventing questionnaire completion
Acute relapse or hospitalization due to exacerbation within the last month
Severe comorbid neurological, psychiatric, or systemic disease affecting assessments
Caregiver <18 years old or not providing regular care
Trial population
Multiple sclerosis and caregivers
Trial design
Cohort
Cross-sectional
Treatments tested in this trial
No intervention
Other interventionNo intervention
Treatment groups
Trial outcomes
Primary outcomes
Zarit Caregiver Burden Scale (Zarit Burden Interview, ZBI)
Caregiver burden will be assessed using the Zarit Caregiver Burden Scale. Higher scores indicate greater caregiver burden.
Secondary outcomes
Insomnia Severity Index (ISI)
The ISI evaluates the severity of insomnia symptoms. Total scores range from 0 to 28, with higher scores indicating more severe insomnia.
Hospital Anxiety and Depression Scale - Anxiety Subscale (HADS-A)
Scores range from 0 to 21, with higher scores indicating greater anxiety.
Hospital Anxiety and Depression Scale - Depression Subscale (HADS-D)
Scores range from 0 to 21, with higher scores indicating greater depressive symptoms.
Expanded Disability Status Scale (EDSS)
The EDSS evaluates disability in multiple sclerosis patients, ranging from 0 (normal neurological exam) to 10 (death due to MS).
Sponsors and contacts
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