Carotenoids in the Skin and Immune Aging
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorStanford University
About this trial
This study aims to examine the connection between the level of carotenoids in the skin and a number of immune related health parameters.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Willing and able to provide written informed consent
Age 18-30 years OR 65 years and older
Healthy individuals without uncontrolled medical conditions (over the counter inhaled and topical steroids allowed)
Fiitzpatrick I-VI (all skin types)
Disqualifiers
Pregnant or breastfeeding
uncontrolled medical conditions
Skin conditions on the upper extremity that would interfere with skin measurements of carotenoid levels such as active atopic dermatitis or psoriasis
Concurrent use of medications that affect the immune system, within 4 weeks of enrollment (eg. prednisone, biologics, methotrexate, rapamycin, prescription topical steroids, prescription inhaled steroids, others)
Trial population
Healthy individuals who are either between 18 to 30 years old or over 65 years old.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
40 Participants
are grouped into 2 trial groupsGroup A: Young adult
Group B: Older adult
Trial outcomes
Primary outcomes
1
Skin carotenoid levels and skin aging features
We will assess the skin carotenoid levels' correlation with skin aging features, such as wrinkles, fine lines, and age spots.
Time frame
one daySecondary outcomes
1
Skin carotenoid levels and biomarkers of aging
We will assess the skin carotenoid levels' correlation with biomarkers associated with aging, such as C-reactive protein, telomere length, telomerase activity etc.
Time frame
one day2
Skin carotenoid levels and self-reported perception of health
We will assess the skin carotenoid levels' correlation with self reported scores on general health and health beliefs, incidence of respiratory, gut and skin allergy symptoms, and sleep quality.
Time frame
2 weeksSponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov