Carotid Doppler Changes After Passive Leg Raising for Prediction of Post-Induction Hypotension in Gastrointestinal Tumor Surgery

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorAnkara City Hospital Bilkent

About this trial

This prospective study aims to investigate the role of the passive leg raise maneuver prior to anesthesia induction in predicting post-induction hypotension among elective gastrointestinal tumor surgery patients using carotid artery Doppler parameters.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Adults aged 18 years or older

Patients scheduled for elective gastrointestinal tumor surgery

Surgery planned under general anesthesia

Body mass index (BMI) <40 kg/m²

Disqualifiers

Refusal to participate or inability to obtain written informed consent

BMI ≥40 kg/m²

Pregnancy

Emergency surgery

Trial population

Adults aged 18 years or older who are scheduled for elective gastrointestinal tumor surgery under general anesthesia. Eligible participants will be ASA physical status I-III and have a BMI \<40 kg/m². Both sexes will be eligible.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

99 Participants
are grouped into 1 trial group
Group A: Elective Gastrointestinal tumor surgery group

Trial outcomes

Primary outcomes

1

Predictive performance of dynamic changes in carotid Doppler parameters (ΔVTI, ΔPSV, ΔFTc) for post-induction hypotension

Evaluation of the predictive performance of percentage changes in carotid artery velocity time integral (ΔVTI), peak systolic velocity (ΔPSV), and corrected flow time (ΔFTc) after passive leg raising maneuver for post-induction hypotension

Time frame
From pre-induction passive leg raising assessment to 20 minutes after general anesthesia induction

Secondary outcomes

1

Association of baseline carotid Doppler parameters with post-induction hypotension

Evaluation of the association between baseline carotid Doppler parameters (VTI, PSV, and FTc) and the development of post-induction hypotension.

Time frame
From pre-induction assessment to 20 minutes after general anesthesia induction
2

Cut-off values of changes in carotid Doppler parameters for prediction of post-induction hypotension

Determination of the optimal cut-off values of ΔVTI, ΔPSV, and ΔFTc for predicting post-induction hypotension.

Time frame
From pre-induction passive leg raising assessment to 20 minutes after general anesthesia induction
3

Association of carotid Doppler changes with duration and severity of hypotension

Evaluation of the association between ΔVTI, ΔPSV, and ΔFTc and the duration and severity of post-induction hypotension.

Time frame
From general anesthesia induction to 20 minutes post-induction
4

Association of carotid Doppler changes with vasopressor requirement

Evaluation of the association between ΔVTI, ΔPSV, and ΔFTc and the requirement for vasopressor treatment after anesthesia induction.

Time frame
From general anesthesia induction to 20 minutes post-induction

Other outcomes

Sponsors and contacts

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