Caval Aorta Index for Fluid Optimization in Traumatic Brain Injury
ConditionFluid Balance
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-60
SponsorMansoura University
About this trial
Traumatic brain injury is a leading cause of death and disability in trauma patients. As the primary injury cannot be reversed; management strategies must focus on preventing secondary injury by avoiding hypotension and hypoxia besides, maintaining appropriate cerebral perfusion pressure, which is a surrogate for cerebral blood flow.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
None
Disqualifiers
None
Trial design
Design model
Parallel
Treatments tested in this trial
ultrasound measurement of caval aorta index
Procedure/Surgeryultrasound measurement of caval aorta index
control group
Other interventionfixed fluid prescription
Treatment groups
92 Participants
are divided into 2 treatment groupsGroup A: Control groupOther 1 intervention
Group B: ultrasound-guided caval-aorta index groupExperimental treatment 1 intervention
Trial outcomes
Primary outcomes
1
fluid balance
the difference between fluid input and fluid loss
Time frame
after 96 hours from the admissionSecondary outcomes
1
Urine output
mL
Time frame
Daily for 7 weeks2
Central Venous Pressure (CVP) measurements
cm H2O
Time frame
Daily every 6 hours for 7 days3
Frequency and duration of hypotension
systolic blood pressure less than 90 mmhg
Time frame
within first 7 days4
Glasgow Coma Scale
range from 3-to-15
Time frame
daily within first 7 daysSponsors and contacts
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Source ClinicalTrials.gov