Cerebellum and Autism: Regional Specialization for Social and Executive Functions
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-35
SponsorAmerican University
About this trial
The goal of this study is to determine the impact of neuromodulation to the cerebellum on social and executive functions in neurotypical young adults and young adults with autism.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Aged 18-35
Able to provide written, informed consent
NIH Toolbox age-adjusted Cognitive Function Composite standard score ≥ 85
Native English speaker
Disqualifiers
Age <18 or >35
NIH Toolbox age-adjusted Cognitive Function Composite standard score < 85
Contraindications for MRI or neuromodulation with tDCS (e.g. metal in body, pacemaker or other implanted device, history of seizure, claustrophobia)
Current or prior history of neurological or neurodevelopmental condition or brain injury
Trial design
Design model
Parallel
Treatments tested in this trial
Transcranial direct current stimulation
DeviceTDCS involves applying small (1-2 mA) electric currents to the scalp in order to transiently modify local neuronal electrical potentials in the brain.
Treatment groups
80 Participants
are divided into 2 treatment groupsGroup A: Right cerebellumExperimental treatment 1 intervention
Group B: Posterior vermisExperimental treatment 1 intervention
Trial outcomes
Primary outcomes
1
Reading the Mind in the Eyes Test Adult Version
Time frame
Within 30min post-tDCS2
Cyberball social ball-playing task
Time frame
Within 30min post-tDCS3
Flexible Item Selection Test
Time frame
Within 30min post-tDCS4
Functional MRI data
Functional MRI task data and resting state functional connectivity data
Time frame
Within 45min post-tDCSSponsors and contacts
Click on the lead sponsor to view all of their trials.
American University
Lead sponsor
National Institutes of Health (NIH)
Collaborator
National Institute of Mental Health (NIMH)
Collaborator
Source ClinicalTrials.gov