About this trial
for patients connected to VA ECMO due to cardiogenic shock, monitoring:
1. Cerebral Oximetry 2. ECMO Parameters ECMO blood flow (L/min) every 12 hours. Sweep gas flow Cannulation configuration 3. Pulmonary Artery Catheter Data and hemodynamics:
Cardiac output / cardiac index, SvO₂, Central venous pressure (CVP). 4. other variables: P/F ratio, MAP, Heart rate, Arterial blood gases, hemoglobin, Lactate, Vasopressor / inotrope doses and Sedation score (RASS). 5. Echocardiography parameters: recorded every 12 hours. LV ejection fraction. LVOT VTi. LVED dimension. Aortic valve opening. 6. Follow-up data:
* ECMO duration. * Need for oxygen therapy/mechanical ventilation. * ICU survival.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age ≥ 18 years
Patients supported with veno-arterial ECMO.
Presence of a pulmonary artery catheter.
Expected ECMO support ≥ 24 hours.
Disqualifiers
Pre-existing severe neurological injury (e.g. massive stroke, traumatic brain injury).
Intracranial pathology affecting NIRS reliability.
Facial or scalp conditions preventing NIRS probe placement.
ECMO duration < 48 hours.
Trial population
patient, aged more than 18 years old with cardiogenic shock unresponsive to conventional medical treatment and supported with VA ECMO.
Trial design
Cohort
Prospective
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
correlation between native cardiac output/ Extracorporeal membrane oxygenation flow ratio and regional cerebral tissue oxygen saturation
Locations
Sponsors and contacts
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Assiut University
Lead sponsor
Cairo University/ECMO unit
Collaborator
This trial is not recruiting at the moment. You can still explore other options: