Health TrialsbyHealthPanel

Cerebrospinal Fluid Biomarkers for Brain Tumors

ConditionCentral Nervous System Neoplasm
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeNot listed
SponsorMayo Clinic

About this trial

This study examines cerebrospinal biomarkers in patients with brain tumors. A biomarker is a measurable indicator of the severity or presence of your disease state. Collecting and storing samples of cerebrospinal fluid from patients with brain tumors to study in the laboratory may help doctors develop new strategies to better diagnose, monitor, and treat brain tumors.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Any evidence of neoplasm involving the central nervous system (CNS) or its adjacent structures in contact with CSF. Such lesions may include but are not limited to intra-axial or extra-axial lesions, which could be benign, malignant or as yet undefined, involving the brain, spine, meninges, nerves, or vasculature or supporting structures

Subjects must be 18 years of age or older

Disqualifiers

Patients who are under 18 years of age or are a member of a vulnerable population will be excluded from this study

Pregnant women or women who may be pregnant are specifically excluded from study participation

Exception will be granted for patients with diminished capacity to consent if a legally authorized representative is available

Patients without clinical or radiographic evidence of a potentially neoplastic CNS lesion will be excluded

Trial population

Patients with known or suspected brain tumors.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • Biospecimen Collection

    Procedure/Surgery

    Undergo collection of CSF samples

  • Electronic Health Record Review

    Other intervention

    Review of medical records

Treatment groups

400 Participants
are divided into 1 treatment group
Group A: Basic science (biospecimen collection)2 interventions

Trial outcomes

Primary outcomes

1

Collection cerebrospinal fluid (CSF) samples that can provide a resource to the research community for biomarker discovery

Time frame
Up to study completion

Secondary outcomes

1

Feasibility of serial cerebrospinal fluid (CSF) sampling

Time frame
Up to study completion

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Mayo Clinic

Lead sponsor

National Institute of Neurological Disorders and Stroke (NINDS)

Collaborator

Source ClinicalTrials.gov
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