Health TrialsbyHealthPanel

Cervical/Thoracic Neuromodulation and Nociceptive Processing

ConditionNociceptive Pain
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-40
SponsorUniversité Catholique de Louvain

About this trial

Several studies have demonstrated that direct currents delivered through the skin at the level of the low-thoracic spinal cord can influence spinal cord function. In human volunteers, anodal low-thoracic transcutaneous spinal direct current stimulation (tsDCS) alters spinal processing of nociceptive inputs. Whether cervical tsDCS is able to do the same is less well known. In this double-blinded, sham-controlled and cross-over trial, the investigators will compare the effects on the nociceptive processing of healthy volunteers of cervical and low-thoracic tsDCS.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

None

Disqualifiers

Known medical conditions (e.g., diabetes, neuropathy, psychiatric disorders, seizure, migraine, pacemaker or other implanted medical devices...)

Use of any medication (except contraception)

Trial design

Design model

Crossover

Treatments tested in this trial

  • cervical a-tsDCS

    Device

    Anodal transcutaneous spinal direct current stimulation (a-tsDCS)

  • thoracic a-tsDCS

    Device

    Anodal transcutaneous spinal direct current stimulation (a-tsDCS)

  • sham tsDCS

    Device

    Sham transcutaneous spinal direct current stimulation (s-tsDCS)

Treatment groups

24 Participants
are divided into 3 treatment groups
Group A: Anodal cervical tsDCSExperimental treatment 1 intervention
Group B: Anodal thoracic tsDCSExperimental treatment 1 intervention
Group C: Sham tsDCSSham comparator 1 intervention

Trial outcomes

Primary outcomes

1

Change in contact-heat evoked potentials amplitude

N2 amplitude

Time frame
Throughout the entire study, approximately during 6 months

Secondary outcomes

1

Change in intensity of perception to contact-heat nociceptive stimuli

Numerical rating scale (0-100)

Time frame
Throughout the entire study, approximately during 6 months
2

Change in skin temperature

Temperature (°C)

Time frame
Throughout the entire study, approximately during 6 months
3

Change in cutaneous blood flow

LDF flow (PU)

Time frame
Throughout the entire study, approximately during 6 months

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Université Catholique de Louvain

Lead sponsor

Source ClinicalTrials.gov
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