Health TrialsbyHealthPanel

Cesarean Anesthesia Blood Gas

ConditionCesarean Delivery
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18+
SponsorBagcilar Training and Research Hospital

About this trial

This prospective observational cohort study will evaluate maternal and fetal blood gas parameters in women undergoing cesarean delivery under spinal or general anesthesia. Maternal venous blood samples will be obtained immediately before anesthesia induction, and umbilical arterial blood samples will be obtained after delivery and cord clamping. Blood gas parameters, including pH, pCO2, pO2, bicarbonate, base excess, lactate, and fetal carboxyhemoglobin levels, will be compared between the spinal and general anesthesia groups. The study will also evaluate maternal-fetal blood gas gradients, Apgar scores, neonatal intensive care requirements, and the relationship between smoking exposure and fetal carboxyhemoglobin levels.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Adult women undergoing cesarean delivery at the study center.

Patients receiving spinal or general anesthesia for cesarean delivery.

Disqualifiers

Patients who are not eligible for participation according to the study protocol.

Patients in whom spinal anesthesia is converted to general anesthesia because of inadequate spinal block and pain during surgery.

Trial population

Pregnant women undergoing cesarean delivery at the Obstetrics and Gynecology Clinic of Bagcilar Training and Research Hospital. The study is a prospective observational cohort comparing maternal and fetal blood gas parameters and fetal carboxyhemoglobin levels according to the observed anesthesia technique (spinal or general anesthesia).

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • Anesthesia Technique

    Other intervention

    Observed anesthesia technique in women undergoing cesarean delivery. Participants received either spinal anesthesia or general anesthesia as part of routine clinical care; the anesthesia technique was not assigned by the study.

Treatment groups

134 Participants
are divided into 2 treatment groups
Group A: Spinal Anesthesia1 intervention
Group B: General Anesthesia1 intervention

Trial outcomes

Primary outcomes

1

Umbilical artery pH

Umbilical arterial pH measured after delivery and cord clamping.

Time frame
Immediately after delivery

Secondary outcomes

1

Maternal venous pH

Maternal venous pH measured immediately before anesthesia induction.

Time frame
Immediately before anesthesia induction
2

Umbilical artery pCO2

Umbilical arterial pCO2 measured after delivery and cord clamping.

Time frame
Immediately after delivery
3

Umbilical artery pO2

Umbilical arterial pO2 measured after delivery and cord clamping.

Time frame
Immediately after delivery
4

Maternal venous pCO2

Maternal venous pCO2 measured immediately before anesthesia induction

Time frame
Immediately before anesthesia induction

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Bagcilar Training and Research Hospital

Lead sponsor

Source ClinicalTrials.gov
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