About this trial
Patients with bloodstream infections (sepsis) have been found in prior studies to have infection-related heart dysfunction, even if they did not have preexisting heart problems. Factors related to the infection may cause the heart to not pump as well as it should, causing critical illness in the form of low blood pressure (shock) and heart failure. Ultrasound is frequently used in the emergency department to evaluate why a patient might have low blood pressure. Part of that evaluation may include obtaining ultrasound images and making measurements about how well or poorly the heart is pumping. The investigators will evaluate a certain measurement that relates to cardiac function, determine how it changes in patients before and after they are treated for septic shock. This will involve placing an ultrasound probe on the patient's chest, measuring the upward and downward movement of the mitral valve, the mitral annulus systolic plane excursion (MAPSE), and comparing the measurements before and after treatment is started. The investigators are attempting to determine if this measurement improves before and after treatment.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Diagnosis of Sepsis or Septic Shock
Disqualifiers
Age equal to or less than 17
patient in the emergency department
Unable to perform POCUS exam due to medical necessity
Patients without sepsis
Trial population
adult emergency department patients who present with sepsis
Trial design
Cohort
Prospective
Treatments tested in this trial
Treatment of Sepsis
Other interventionPatients will have standard care of sepsis
Treatment groups
Trial outcomes
Primary outcomes
Change in MAPSE measurement
Does the MAPSE change after treatment of MAPSE
Sponsors and contacts
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