Changes of Soft Tissue Grafting: A Randomized Study
ConditionGingival Recession
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorTufts University
About this trial
To correct gum recession, patient's own tissue from the roof of the mouth is harvested and placed where there is root exposed. This is considered gold standard of treatment. Sometimes patient don't want to have second surgical site in their mouth and at the same time do not want to use alternative tissue from human or animal donor. Using patients' blood and preparing it as a membrane is the next best thing to correct gum recession.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Adults 18yrs or older
Need of MG-tx for 2 or more sites for root coverage RT I and II (Cairo classification)
Class A +/-
No class V restoration present
Disqualifiers
Patients who do not consent to recommended therapy
Patients who smoke
Patients who will not be able to comply with follow up protocols
Those who self report that they are pregnant.
Trial design
Design model
Single group
Treatments tested in this trial
Split Mouth Design
Procedure/SurgeryPRF on one side of mouth and CTG on the other side of participant's mouth.
Treatment groups
50 Participants
are divided into 1 treatment groupGroup A: All ParticipantsExperimental treatment 1 intervention
Trial outcomes
Primary outcomes
1
Compare autologous PRF & Autogenous CTG
Primary objective of this study is to compare in a split-mouth study the effectiveness of CTG vs. PRF in soft tissue augmentation and volume stability of each treatment modality in correcting the Cairo Class I, II defects in Periodontally affected patients
Time frame
5 yearsSponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov