Health TrialsbyHealthPanel

Characteristics, Phenotypes, and TRAITS of Heart Failure With Preserved Ejection Fraction (TRAITS-HFpEF)

ConditionHeart Failure With Preserved Ejection Fraction (HFpEF)
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorManchester University NHS Foundation Trust

About this trial

Heart failure with preserved ejection fraction (HFpEF), a certain type of heart failure, occurs when the heart doesn't pump blood around the body properly. It can cause breathlessness, tiredness, and swollen feet or ankles. It is not clear why people develop HFpEF and treatment options are very limited.

TRAITS-HFpEF is a study that aims to understand why people develop HFpEF, identify new tests and treatments, and gain information on the life expectancy of people living with this condition. It will do this by routinely collecting information on people attending a specialised outpatient HFpEF clinic.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients attending the HFpEF clinic at MFT.

Disqualifiers

Age < 18 years

Imprisonment

Inability to provide full written or verbal informed consent in English

Trial population

All individuals will be considered for inclusion in this study regardless of age, disability, gender reassignment, marriage and civil partnership, pregnancy and maternity, race, religion and belief, sex, and sexual orientation except where the study inclusion and exclusion criteria explicitly state otherwise.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Trial outcomes

Primary outcomes

1

Composite of all cause mortality and hospitalisation for heart failure

Time frame
7.5 years

Secondary outcomes

1

All cause mortality

Time frame
7.5 years
2

Hospitalisation for heart failure

Time frame
7.5 years
3

Identification of HFpEF phenotypes

Machine Learning analysis will be implemented to assess relationships between multiple clinical variables and the aforementioned outcome measures to identify novel HFpEF phenotypes.

Time frame
7.5 years

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Manchester University NHS Foundation Trust

Lead sponsor

Source ClinicalTrials.gov
Apply now