Characteristics, Treatment Patterns and Outcomes for Patients With Surgically Resected Lung Cancers

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorCancer Institute and Hospital, Chinese Academy of Medical Sciences

About this trial

This study is a multi-center, observational, real-world study for patients with resected lung cancers in China. With the help of a properly designed data processing algorithm and extensively performed data quality assurance, this study aims to harness the potential of real-world big data to (1) describe characteristics and treatment patterns and their evolving trends; (2) discover features associated with overall survival; and (3) address recently-emerging clinical questions.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age above 18.

Have received surgical resection for lung malignancies.

Disqualifiers

Participants whose data are of low quality, poor completeness or poor internal linkage.

Trial population

Participants eligible for this study would be screened from consecutive patients who received surgical resection for lung malignancies in participating medical centers during the designed study period.

Trial design

Design model

Cohort

Time perspective

Other

Treatments tested in this trial

Not listed

Trial groups

60,000 Participants
are grouped into 1 trial group
Group A: Patients with surgically resected lung cancer

Trial outcomes

Primary outcomes

1

Overall survival

Time from surgery to death from any cause.

Time frame
January 2014 to December 2031

Secondary outcomes

1

Baseline characteristics of included participants

Demographics, symptoms at diagnosis, tobacco exposure, family history, previous medical history, etc.

Time frame
January 2014 to December 2028
2

Treatment patterns of included participants

Extent of lung resection and lymph node dissection, application of certain surgical techniques or not; application of chemotherapy, targeted therapy, immunotherapy and/or radiotherapy before and/or after surgery.

Time frame
January 2014 to December 2028
3

Pathological characteristics of included participants

Location, size, classification, presence or absence of certain pathological features of resected tumor(s); number of metastasized and dissected lymph nodes in each station.

Time frame
January 2014 to December 2028
4

Features associated with overall survival

Features within the range of collected baseline characteristics, treatment patterns and pathological characteristics that are associated with overall survival.

Time frame
First analysis is anticipated to be performed from April to August 2024; the final analysis is anticipated in 2032.

Other outcomes

Sponsors and contacts

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