Chest CT Scan in Pulmonary Mucormycosis: Prognostic Value
ConditionPulmonary Mucormycosis
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity Hospital, Strasbourg, France
About this trial
Invasive pulmonary fungal infections caused by Mucorales are rare but severe and rapidly progressive, affecting immunocompromised patients. The role of chest imaging in their diagnosis is well established in the 2020 EORTC/MSGERC criteria, and its use is almost systematic. However, the progression of lung parenchymal involvement and any potential prognostic radiological patterns in the follow-up of these infections are less well understood. This research aims to identify imaging characteristics predictive of favorable or unfavorable outcomes in infected patients, in order to better tailor follow-up and therapeutic options.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patients aged 18 years or older
Treated at Strasbourg University Hospital between January 1, 2009, and June 3, 2025
With a diagnosis of probable or proven invasive pulmonary infection with Mucorales according to the 2020 EORTC/MSGERC criteria
Having undergone at least one CT scan including the thoracic region
Disqualifiers
No CT scan including the thoracic region
No diagnosis of probable or proven invasive pulmonary infection with Mucorales (EORTC/MSGERC 2020 criteria)
Trial population
Adult patients with a diagnosis of probable or proven invasive pulmonary infection with Mucorales according to the 2020 EORTC/MSGERC criteria
Trial design
Design model
Case-only
Time perspective
Retrospective
Treatments tested in this trial
Not listed
Trial groups
No trial groups listed
Trial outcomes
Primary outcomes
1
Death rate in patients with probable or proven invasive Mucorales infection
Death rate at day 15 in patients with probable or proven invasive Mucorales infection
Time frame
Day 15 after infectionSponsors and contacts
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Source ClinicalTrials.gov