Children's Health, Respiratory Inflammation and Short-term Air Pollution
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age7-11
SponsorQueen Mary University of London
About this trial
The goal of this study is to see if physical activity in high air pollution is worse than rest in high air pollution.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Attending schools in Central and East London that have been recruited to the study
Disqualifiers
Not able to engage with PE lessons on safety grounds, reported by their parents.
Children with learning or physical disabilities sufficient for them to be unable to give informed assent to the study, or to carry out study procedures
Trial design
Design model
Single group
Treatments tested in this trial
science lesson
Behavioralchildren have a 90 minute science lesson outdoors
PE Lesson
BehavioralCHildren have a 90 minute PE lesson outdoors
Treatment groups
330 Participants
are divided into 2 treatment groupsGroup A: Physical activityExperimental treatment 1 intervention
Group B: SedenaryActive comparator 1 intervention
Trial outcomes
Primary outcomes
1
"Airway resistance" measured by Oscillometry at R5
measured as oscillometery R5
Time frame
Pre-24 hour post exposureSecondary outcomes
1
"Small airway resistance" measured by Oscillometry at R5-20
Measured by oscillometry R5-20
Time frame
pre- 24 hour post exposure2
Immune responses as measured by Il6 in nasal lavage
Immune response as measured by Il6 in nasal lavage
Time frame
pre-24 hour post exposureSponsors and contacts
Click on the lead sponsor to view all of their trials.
Queen Mary University of London
Lead sponsor
Imperial College London
Collaborator
Source ClinicalTrials.gov