About this trial
The goal of this observational study is to learn about the treatment strategies for tumor in sellar region with unruptured intracranial aneurysms in the Chinese population. The main question it aims to answer is: For patients with tumor in sellar region combined with unruptured intracranial aneurysms, which condition should be treated first?
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Preoperative enhanced head MRI showing a suspected diagnosis of a sella region lesion, and preoperative head CTA/DSA confirming an unruptured intracranial aneurysm.
Patients with primary sella region tumor and unruptured intracranial aneurysms that have not previously accepted surgical treatment.
Patients with tumor in sellar region requiring craniotomy or endoscopic transnasal surgery and/or an aneurysm requiring craniotomy, endovascular treatment, or observation only.
The patients are in good general health, without severe underlying medical conditions, and capable of tolerating surgical treatment.
Disqualifiers
Patients with recurrent sella region tumors.
Patients with previously treated intracranial aneurysm.
Pregnant or breastfeeding women.
Any other condition that, in the investigator's judgment, makes the patient unsuitable for trial participation.
Trial population
Patients diagnosed of tumor in sellar region with unruptured intracranial aneurysms in the Chinese population
Trial design
Case-only
Prospective
Treatments tested in this trial
Tumor resection followed by aneurysm treatment
Procedure/SurgeryTumor resection followed by aneurysm treatment
Aneurysm treatment followed by tumor resection
Procedure/SurgeryAneurysm treatment followed by tumor resection
Observation
Other interventionTumor resection without aneurysm treatment but observation
Treatment groups
Trial outcomes
Primary outcomes
Aneurysm progression
The diameter of aneurysm neck, the diameter of aneurysm dome, the volume of aneurysm, aneurysm rupture status
Tumor related complication and progression
The related complication and progression of tumor in sellar region: pituitary hormone level, visual acuity and visual field, hydrocephalus and tumor recurrence.
Sponsors and contacts
Click on the lead sponsor to view all of their trials.
Cheng sen
Lead sponsor
Capital Medical University
Sponsor institution
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Collaborator
West China Hospital
Collaborator
Xijing Hospital
Collaborator
Shandong Provincial Hospital
Collaborator
The First Affiliated Hospital of Anhui Medical University
Collaborator
First Affiliated Hospital of Chongqing Medical University
Collaborator
Shengjing Hospital
Collaborator
Lanzhou University Second Hospital
Collaborator
The First Hospital of Jilin University
Collaborator
People's Hospital of Xinjiang Uygur Autonomous Region
Collaborator
Guangdong Provincial Hospital of Traditional Chinese Medicine
Collaborator
Huashan Hospital
Collaborator
Jinling Hospital, China
Collaborator
This trial is not recruiting at the moment. You can still explore other options: