About this trial
The PFA (platelet function analysis) test is prescribed for the exploration of primary hemostasis and the study of platelet-willebrand factor interaction. It is performed using citrated blood, with technical difficulties and frequent alarms that may be linked to the choice of anticoagulant (citrate). It is proposed to compare the results obtained with a conventional citrate tube and a BAPA tube, which is an anticoagulant used in clinical research and which blocks coagulation by another mechanism that would have less impact on blood platelets.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Person having given their non-opposition
Person of legal age
Person receiving a haemostasis consultation at the haemophilia and haemorrhagic diseases treatment center followed by a blood sample with a PFA test prescribed by the doctor (the test is not added for the study).
Disqualifiers
persons under legal protection (curatorship, guardianship)
persons subject to a court protection order
pregnant, parturient or breast-feeding women
adult incapable or unable to give consent
Trial population
Patients requiring a PFA test
Trial design
Cohort
Prospective
Treatments tested in this trial
Sampling of 3 additional BAPA tubes
Biological/Vaccinethe 3 additional tubes will be taken at the same time as the blood sample taken for the routine PFA test
Treatment groups
Trial outcomes
Primary outcomes
Occlusion time measurement
Measurement of the occlusion times of the 2 cartridges (collagen/ADP and collagen/epinephrine) with the classic 0.109M citrate tube and the BAPA tube, with any PLC alarms and observation of the stained blood smears.
Sponsors and contacts
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