Health TrialsbyHealthPanel

Cholera-Hospital-Based-Intervention-for-7-Days (CHoBI7) Water, Sanitation, and Hygiene (WASH) Case Area Targeted Intervention (CATI)

ConditionsCholeraDiarrhea
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
AgeNot listed
SponsorJohns Hopkins Bloomberg School of Public Health

About this trial

Objective: The investigators objective is to develop and evaluate the effectiveness of a case area targeted water, sanitation, and hygiene (WASH) intervention in reducing cholera infections and increasing sustained WASH behaviors in transmission hotspots in a ring around cholera cases.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Index cholera patient have no running water inside of their home

Disqualifiers

No one will be excluded because of age, sex, religion, or sexual preference

Trial design

Design model

Parallel

Treatments tested in this trial

  • Cholera-Hospital-Based-Intervention-for-7-Days (CHoBI7) CATI

    Behavioral

    The CHoBI7 program is during group sessions by a health promoter to those residing in a ring around a cholera patient reinforced through weekly voice and text messages from the CHoBI7 mHealth program over 12 months on the recommended water, sanitation, and hygiene behaviors.

  • Standard message

    Behavioral

    Standard message given in the Democratic Republic of the Congo to diarrhea patients at health facility discharge on use of oral rehydration solution

Treatment groups

3,140 Participants
are divided into 2 treatment groups
Group A: Cholera-Hospital-Based-Intervention-for-7-Days (CHoBI7) CATIExperimental treatment 1 intervention
Group B: Standard Message ArmActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Number of non-baseline cholera infections among individuals residing in a ring around cholera patients

cholera infection assessed by bacterial culture and/or vibriocidal antibody titer

Time frame
1 month

Secondary outcomes

1

Diarrhea among individuals residing in a ring around cholera patients

Self-reported or caregiver reported diarrhea (3 or more loose stools for a 24 hour period)

Time frame
12 months
2

Child development for children under 5 years of age as assessed by the Assessed by Extended Age and Stages Assessment Questionnaire (EASQ)

Assessed by Extended Age and Stages Assessment Questionnaire (EASQ)

Time frame
12 Months
3

Rate of Handwashing with soap at stool and food related events

Rate of patient household members handwashing with soap at stool and food related events

Time frame
12 Months
4

Free chlorine concentration (mg/L) in stored drinking water

Free chlorine concentration (mg/L) in stored drinking water

Time frame
12 months

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Johns Hopkins Bloomberg School of Public Health

Lead sponsor

Research Training and Management International (RTMI)

Collaborator

International Centre for Diarrhoeal Disease Research, Bangladesh

Collaborator

National Institute of Allergy and Infectious Diseases (NIAID)

Collaborator

Source ClinicalTrials.gov
Apply now