The aim of the study is to estimate the incidence of CE, evaluate the endometrial microorganism of CE, and investigate the therapeutic benefits of antibiotics for women with unexplained recurrent miscarriage and CE.
Women with a history of 2 or more consecutive miscarriages before 24 weeks of gestation
Women aged 20-45 years old
Uncorrected uterine anomalies, such as the septate or bicornuate uterus, fibroids (submucous/intramural)
Untreated hydrosalpinx
Antiphospholipid syndrome
Known clinical autoimmune disease
Subjects will be identified and recruited from the miscarriage clinic by clinicians and research assistants and research nurse.
Cohort
Prospective
If the CE is high, antibiotics will be given to the patients as usual practice in hospitals.
the incidence of chronic endometritis in local women with unexplained recurrent miscarriage
the incidence of chronic endometritis in local women with unexplained recurrent miscarriage
Investigate the spectrum of endometrial microorganisms associated with chronic endometritis in this population
Investigate the spectrum of endometrial microorganisms associated with chronic endometritis in this population
Assess the clinical pregnancy outcomes between cured CE group and non-CE group
Assess the clinical pregnancy outcomes in both cured CE group and non-CE group
Click on the lead sponsor to view all of their trials.
