Chronic Total Occlusion and Triglyceride-Glucose Index

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorKırıkkale University

About this trial

We retrospectively analyzed 200 CAD patients undergoing coronary angiography between 2026-2027. Patients were grouped by CTO presence. Clinical and laboratory parameters were compared, and logistic regression was performed to identify independent predictors.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Adults ≥18 years of age, patients undergoing coronary angiography, non-obese individuals

Disqualifiers

Patients <18 years of age, history of atrial fibrillation, pacemaker implantation, asthma, pulmonary hypertension, pregnancy, anemia, malignancy, rheumatoid arthritis, or peripheral artery disease, obesity (BMI >30 kg/m²), inaccessible patient records

Trial population

The study population will consist of adult patients (≥18 years of age) undergoing coronary angiography, who will be divided into two groups according to the presence or absence of chronic total occlusion (CTO).

Trial design

Design model

Cohort

Time perspective

Cross-sectional

Treatments tested in this trial

  • triglyceride-glucose (TyG) index was calculated from routinely obtained blood samples using the formula: Triglyceride (mg/dL) × Glucose (mg/dL) / 2.

    Diagnostic test

    As no previous studies have demonstrated the predictive value of the TyG index for chronic total occlusion (CTO), the present investigation provides a novel contribution to the literature. We hypothesize that the triglyceride-glucose (TyG) index will be significantly higher in patients with chronic total occlusion (CTO) compared to those without CTO.

Treatment groups

200 Participants
are divided into 2 treatment groups
Group A: Non CTO1 intervention
Group B: CTO1 intervention

Trial outcomes

Primary outcomes

1

The primary outcome measure will be the difference in the triglyceride-glucose (TyG) index between patients with chronic total occlusion (CTO) and those without CTO, assessed from routinely obtained blood samples.

Time frame
1 Year

Secondary outcomes

Other outcomes

Sponsors and contacts

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