CITE: Clinical Inference Tethered to Evidence - a Retrieve-and-verify Layer for AI Care Plans
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorWaymark
About this trial
This trial evaluates CITE, a retrieve-and-verify layer that audits an AI-generated care plan against a full-text evidence corpus and flags patient-specific codifiable safety hazards to the clinician. The co-primary outcomes are how accurately CITE flags these hazards (sensitivity and specificity versus blinded clinician adjudication) and its clinician alert burden and acceptance, compared with AI care plans using safety guardrails alone and with unassisted clinician care, in Medicaid primary care.
Eligibility criteria
Qualifiers
Age 18 years or older.
Medicaid-enrolled and attributed to a participating Waymark primary care site.
Primary care encounter that requires clinical reasoning (not administrative-only).
English-language clinical documentation.
Disqualifiers
Age less than 18 years.
Hospice or palliative-care-exclusive care plan.
Administrative-only or pharmacy-only encounter that does not surface a clinical decision to the supervising clinician.
Encounter where the supervising clinician is the principal investigator.
Trial design
Treatments tested in this trial
- CITE evidence-grounding retrieve-and-verify layer
- AI care plan with safety guardrails
Treatment groups
240 Participants
are divided into 3 treatment groupsLocations
Sponsors and collaborators
Waymark
Lead sponsor
University of California, San Francisco
Sponsor institution
University of California, San Francisco
Collaborator
Source ClinicalTrials.gov