Climate Change Trends and Their Impact on the Seasonal Upper Respiratory Tract Disease Burden

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeNot listed
SponsorBarzilai Medical Center

About this trial

Investigators assume that global climate changes can influence upper respiratory tract infection peak prevalence, which may have significant clinical implication, for example, by adjusting seasonal Influenzas' vaccine timing. Therefore, the investigators will collect data from electronic medical database about patients tested positive for winter seasonal respiratory tract viruses from 2022 and compare the incidence to the meteorological profile of that season.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

All patient with a positive nasopharyngeal swab for a respiratory virus

Disqualifiers

No medical record available

Trial population

All patients with a positive nasopharyngeal swab for a respiratory virus - Influenza, RSV, Para-Influenza, Human MetaPneumoVirus, Rhinovirus.

Trial design

Design model

Case-only

Time perspective

Retrospective

Treatments tested in this trial

  • No Intervention: Observational Cohort

    Other intervention

    No intervention, observational retrospective study.

Treatment groups

5,000 Participants
are divided into 1 treatment group
Group A: URTI infection1 intervention

Trial outcomes

Primary outcomes

1

Incidence

Examining the incidence of severe upper respiratory tract illness (requiring hospital visits) in relation to weather changes over the last four seasons.

Time frame
4 winter seasons, from 2022 to 2026.

Secondary outcomes

1

Morbidity

Analysis of winter morbidity trends among patients presenting to the hospital with Influenza. Including severity of illness (need for ICU admission, mechanical ventilation and/or inotropes assistance).

Time frame
4 winter seasons, 2022 to 2026.
2

Mortality

Analysis of winter mortality trends among patients presenting to the hospital with Influenza. Including mortality during hospitalization or within 30 days.

Time frame
4 winter seasons 2022-2026
3

recurrence

Analysis of upper respiratory tract infection recurrence trends among patients presenting to the hospital with Influenza. Including recurrent admission within 30 days.

Time frame
4 winter seasons, 2022-2026

Other outcomes

Sponsors and contacts

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