Determining Clinical and Cardiopulmonary exercise testing Parameters that may predict Improvement in Capacity After Transcatheter Aortic Valve Implantation
All those patients ≥ 18 years of age with severe aortic stenosis approved for transfemoral TAVI.
Previous syncope
Proven exercise-induced arrhythmias
Previously known dynamic left ventricular outflow tract (LVOT) obstruction, defined as LVOT gradient of ≥ 30 mmHg by echocardiography
Concomitant coronary artery disease pending percutaneous coronary intervention
Patients 18 years of age or older, with severe, non-critical, aortic stenosis who are scheduled for transfemoral TAVI will participate in the study
Cohort
Prospective
Not listed
Delta VO2 max and Delta VO2 at anaerobic threshold
Change in CPET parameters after Transcatheter Aortic valve implantation (TAVI): VO2 max, VO2 at anaerobic threshold
Clinical and functional pre-TAVI factors that predict improvement in functional capacity after TAVI
To identify clinical and functional pre-TAVI factors that predict improvement in functional capacity after TAVI (i.e., VO2 max increase \> 2.5 ml/kg/min or \>10% increase in VO2 max). ml/kg/min or \>10% increase in VO2 max).
Clinical predictors of improvement in quality of life
To identify clinical, echocardiographic and functional pre-TAVI variables that predict improvement in quality of life
pre-TAVI CPET parameters that predict in-hospital complications.
Correlation between pre-TAVI CPET parameters and in-hospital complications.
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