Clinical and Radiographic Outcomes of Alveolar Ridge Preservation

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorFondazione Policlinico Universitario Agostino Gemelli IRCCS

About this trial

Dental implants are considered a predictable rehabilitative option following tooth extraction or in cases of missing teeth. In some situations, the inevitable alveolar ridge resorption that occurs after extraction may make the placement of standard-diameter (\>3.5 mm) or standard-length implants difficult or even impossible without advanced bone augmentation procedures. To counteract post-extraction volumetric bone contraction, alveolar ridge preservation can be performed, consisting of placing a bone graft within the socket walls immediately after tooth extraction. Although this procedure cannot completely prevent dimensional changes, it has been shown to significantly reduce both horizontal and vertical ridge resorption, as reported in the scientific literature. However, there is a lack of clinical and radiographic studies evaluating the outcomes of implant rehabilitation following alveolar ridge preservation with standard-dimension implants in a hospital-based setting.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients requiring alveolar ridge preservation procedures prior to implant rehabilitation of edentulous sites;

Age > 18;

Achievement of FMPS and FMBS ≤ 15%;

Signed written informed consent to participate in the study.

Disqualifiers

Uncontrolled diabetes or hypertension;

Uncontrolled periodontal disease;

Inability to perform consistent and continuous follow-up;

Pregnancy or breastfeeding;

Trial population

Patients aged 18 years and older requiring bone regeneration with an alveolar ridge preservation technique prior to implant rehabilitation will be included in the study.

Trial design

Design model

Case-only

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

50 Participants
are grouped into 1 trial group
Group A: Alveolar ridge preservation

Trial outcomes

Primary outcomes

1

Volumetric analysis

The dimensional change of hard tissues following bone regenerative procedures will be assessed radiographically by measuring horizontal and vertical bone resorption through CBCT comparison in patients treated in a hospital-based setting.

Time frame
From tooth extraction to 6 months of follow up.

Secondary outcomes

1

Esthetic evaluation

Assessed using the PES/WES esthetic index. Scores range from 0 to 14 for the PES and from 0 to 10 for the WES, with higher scores indicating better esthetic outcomes.

Time frame
From tooth extraction to 5 years of follow-up
2

Implant success rate

Absence of biological and technical complications, expressed as a proportion

Time frame
From tooth extraction to 5 years of follow up
3

Implant survival rate

Rate of dental implants remaining in situ, measured as a proportion

Time frame
From tooth extraction to 5 years follow up
4

Prosthesis success rate

Absence of technical complications, expressed as a proportion

Time frame
From tooth extraction to 5 years of follow up

Other outcomes

Sponsors and contacts

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This trial is not recruiting at the moment. You can still explore other options: