About this trial
The aim of the study is to assess the association between bladder sensations progression during bladder filling and severity of Overactive bladder (OAB) in patients with multiple sclerosis.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age ≥ 18
MS according to the 2017 Mac Donald diagnostic criteria
Bladder disorders supposedly related to MS
Indication to perform urodynamics
Disqualifiers
Legal protection
Pregnancy or breastfeeding mother
MS relapse during the past month
Other associated neurological disease
Trial design
Single group
Treatments tested in this trial
Repeated cystometries with bladder sensations assessment
Procedure/SurgeryA second cystometry will be performed to assess bladder sensations reliability. A third cystometry with cognitive task (STROOP test) at the same time will be performed to assess the impact of distractive attentional task on bladder sensations
Treatment groups
Trial outcomes
Primary outcomes
bladder sensation ( area under the sensation-capacity curve (AUC))
The areas under the sensation-capacity curve (AUC) will be calculated for individual participants using the trapezoidal rule for specific capacity ranges.
Secondary outcomes
bladder sensitivity
Bladder sensitivity assessed by the number of steps in the evolution of the need to urinate reported by the patient (number of times the cursor of the analogical scale is moved), during the filling.
Sponsors and contacts
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