Clinical Comprehensive Evaluation of Neuroprotective Drugs for Acute Ischemic Stroke

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorQianfoshan Hospital

About this trial

This study conducted a comprehensive evaluation of commonly used neuroprotective agents in acute ischemic stroke, assessing their real-world value across six dimensions: safety, efficacy, cost-effectiveness, innovativeness, appropriateness, and accessibility. Employing a prospective observational design, it primarily investigates the association of edaravone and dexrazoxane with clinical outcomes in patients with mild-to-moderate stroke, with subgroup analyses performed according to Trial of Org 10172 in Acute Stroke Treatment (TOAST )classification.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

1: Age≥18

Disqualifiers

1: A head CT or MRI scan indicates the presence of intracranial hemorrhagic disease

Trial population

Patients with ischemic stroke

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Trial outcomes

Primary outcomes

1

Proportion of patients with Modified Rankin Scale(mRS )scores of 0-1

Time frame
90 days

Secondary outcomes

1

Proportion of patients with mRS scores of 0-2

Time frame
30 days
2

Percentage reduction in National Institutes of Health Stroke Scale (NIHSS )score compared to pre-treatment

Time frame
90 days after medication

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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