Clinical Evaluation of Two Different Surgical Techniques With PRF in the Treatment of Multiple Gingival Recessions

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorPamukkale University

About this trial

This prospective clinical study aims to evaluate and compare the effectiveness of coronally advanced flap (CAF) and tunnel techniques, both combined with platelet-rich fibrin (PRF), in the treatment of multiple Miller Class I-II gingival recessions. Eleven participants with bilateral defects will be treated using a split-mouth design. Periodontal parameters will be assessed at baseline, 3 months, and 6 months.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Age 18 years or older

Systemically healthy individuals

Presence of bilateral Miller Class I-II multiple gingival recessions

Good oral hygiene and willingness to follow instructions

Disqualifiers

Use of tobacco or smoking

Pregnancy or lactation

Presence of systemic diseases affecting periodontal health

Use of medications that may affect healing (e.g., corticosteroids)

Trial design

Design model

Crossover

Treatments tested in this trial

  • CAF with PRF

    Procedure/Surgery

    Coronally advanced flap technique will be performed to reposition the gingival margin coronally. Platelet-rich fibrin (PRF) membranes will be placed over the exposed root surfaces and stabilized with sutures.

  • Tunnel with PRF

    Procedure/Surgery

    A tunnel or subgingival pouch will be created using microsurgical instruments without vertical incisions. Platelet-rich fibrin (PRF) membranes will be inserted into the tunnel and the gingival tissue will be advanced coronally and sutured to cover the recession.

Treatment groups

10 Participants
are divided into 2 treatment groups
Group A: CAF + PRFExperimental treatment 1 intervention
Group B: Tunnel + PRFExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Change in Recession Height (RH)

Recession height will be measured in millimeters from the cementoenamel junction to the gingival margin using a periodontal probe at baseline and 6 months postoperatively.

Time frame
Baseline and 6 Months

Secondary outcomes

1

Change in Clinical Attachment Level (CAL)

Clinical attachment level will be measured in millimeters using a periodontal probe to assess periodontal healing at different time points.

Time frame
Baseline, 3 Months, and 6 Months

Other outcomes

Sponsors and contacts

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