Clinical Features and Outcomes of CBP Versus Non-CBP in Septic Children
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age28-18
SponsorChildren's Hospital of Fudan University
About this trial
The effect of continuous blood purification (CBP) in children is unclear. Also, the timing of early application is still being explored. In this study, we need to explore the efficacy and the timing of application of CBP in children with sepsis or septic shock.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age of 29d to 18 years old;
Children diagnosed with sepsis requiring blood purification.
Disqualifiers
with a history of a duration of PICU stay <24 h
active bleeding, including cerebral hemorrhage
Trial population
children with sepsis requiring blood purification to prevent or treat fluid overload or to clear cytokines
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
CBP
Procedure/Surgerycontinuous blood purification can prevent or treat fluid overload in children with septic shock or other sepsis-associated organ dysfunction who are unresponsive to fluid restriction and diuretic therapy management of septic AKI patients, particularly those with hemodynamic instability or fluid overload. Also, it can remove cytokines
Treatment groups
90 Participants
are divided into 2 treatment groupsGroup A: sepsis group with CBP1 intervention
Group B: sepsis group without CBP0 interventions
Trial outcomes
Primary outcomes
1
survival rate
The survival rate of children in 28 days after hospital discharge
Time frame
28 days after hospital dischargeSecondary outcomes
1
The creatinine level of non-survival children with sepsis
The creatinine level of non-survival children with sepsis in 28 days after hospital discharge
Time frame
28 days after hospital dischargeSponsors and contacts
Click on the lead sponsor to view all of their trials.
Children's Hospital of Fudan University
Lead sponsor
Shanghai Children's Hospital
Collaborator
Shanghai Children's Medical Center
Collaborator
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Collaborator
Source ClinicalTrials.gov