Clinical Observational Registry of Patients With Left Bundle Branch Block
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorAzienda Ospedaliero Universitaria di Sassari
About this trial
The electromechanical dyssynchrony induced by the presence of LBBB is in some patients, but not all, the cause of progressive left ventricular systolic dysfunction and heart failure.
Aims
1. To investigate the clinical, ECG, imaging-derived features in a large cohort of patients affected by LBBB on ECG. 2. To identify predictors of LBBB-induced LV systolic dysfunction and predictors of outcome in this population. 3. To derive data which may have an impact on therapeutic management.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
LBBB on ECG
Disqualifiers
Previous extensive anterior myocardial infarction
Previous cardiac surgery or transcatheter aortic valve implantation (TAVI)
Congenital structural heart disease
Patients implanted with permanent right ventricular stimulation devices and permanent pacing
Trial population
Patients with LBBB
Trial design
Design model
Case-only
Time perspective
Prospective
Treatments tested in this trial
ECG, Echocardiogram, Magnetic resonance
Diagnostic testClinical and instrumental follow-up
Treatment groups
No treatment groups listed
Trial outcomes
Primary outcomes
1
Left ventricular dysfunction
Echocardiographic left ventricular ejection fraction - EF (%)
Time frame
20 yearsSecondary outcomes
1
Adverse cardiovascular events (e.g., heart failure)
Heart failure (incidence and prevalence) Hospitalizations due to heart failure MACE
Time frame
20 yearsSponsors and contacts
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Source ClinicalTrials.gov