Clinical Outcomes of Cardiovascular Disease
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-80
SponsorXinjiang Medical University
About this trial
This study is a prospective, single center cohort study that primarily registers the clinical characteristics, outcomes, and influencing factors of patients with different types of cardiovascular diseases. Evaluate multiple examination indicators of patients at baseline, 1 year and longer, and follow up on the incidence of major cardiovascular and cerebrovascular adverse events, heart failure readmission, death, and other endpoint events.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Coronary heart disease According to coronary angiography and coronary CTA, at least one coronary artery has a degree of stenosis greater than 50%.
Hypertension Hypertension is defined as office systolic blood pressure is ≥ 140mmHg and/or the diastolic blood pressure is ≥ 90mmHg without the use of antihypertensive drugs.
Heart failure There is a clear history of organic heart disease, clinical symptoms and signs of heart failure, and objective evidence of heart failure.
Cardiomyopathy Including defined dilated cardiomyopathy, hypertrophic cardiomyopathy, restrictive cardiomyopathy, etc.
Disqualifiers
Age<18 years old, or>80 years old.
Patients with various malignant tumors.
Liver dysfunction (defined as ALT or total bilirubin greater than three times the upper normal limit).
Renal insufficiency (defined as blood creatinine exceeding 1.5 times the upper normal limit).
Trial population
The study population mainly includes patients with different types of cardiovascular diseases. Mainly including coronary heart disease, cardiomyopathy, hypertension, heart failure and other diseases.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
No trial groups listed
Trial outcomes
Primary outcomes
1
All cause death
Death caused by various reasons.
Time frame
1 year.2
Cardiac death
Death caused by cardiac reasons.
Time frame
1 year.3
Main adverse cardiovascular events（MACE）
The composite endpoint for hospitalization for heart failure, non fatal myocardial infarction, and cardiac death.
Time frame
1 year.4
Heart failure
Heart failure (HF) is defined according to the diagnostic criteria for HF. Briefly, HF was defined as typical signs and symptoms of HF (NYHA class III or IV), as well as a history of myocardial infarct (MI) or with advanced coronary artery disease including severe 3-vessel disease and chronic total occlusion or other Organic heart disease.
Time frame
1 year.Secondary outcomes
1
Main adverse cardiovascular and cerebrovascular events（MACCE）
The composite endpoint for hospitalization for heart failure, non fatal myocardial infarction, cardiac death, and stroke.
Time frame
1 year.2
Main adverse cardiovascular and cerebrovascular events（MACCE）
The composite endpoint for hospitalization for heart failure, non fatal myocardial infarction, cardiac death, and stroke.
Time frame
3 years.3
All cause death
Death caused by various reasons.
Time frame
3 years.4
Cardiac death
Death caused by cardiac reasons.
Time frame
3 years.Sponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov