Clinical Outcomes of Sutured Versus Sutureless Conjunctival Autograft in Primary Pterygium Excision

ConditionsPterygium of Conjunctiva and Cornea Pterygium of Both Eyes Pterygium

Trial statusNot yet recruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18-60

SponsorAssiut University

About this trial

The goal of this study is to find out if a certain technique in pterygium excision surgery ,using no sutures, is better than the technique mostly used ,which uses sutures.

Investigators aim to find out whether the no sutures technique provides better efficiency and patient satisfaction than the traditional approach. They predict that if this study provides evidence of the advantages of this technique over the one used, surgeons would be encouraged to use it instead. Because not only would the patient benefit, the surgeon also may save operative time and effort used in the technique which uses sutures.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Adults aged between 18-60 years old.

Patients diagnosed with primary Pterygium (Grades 1-4)

Disqualifiers

Patients unable to offer viable consent

Patients with other significant ocular surface diseases, bleeding disorders, or systemic conditions affecting wound healing.)

Recurrent pterygium

Combined ocular surgery

Trial design

Design model

Single group

Treatments tested in this trial

Clinical outcomes of sutured versus sutureless conjunctival autograft in primary pterygium excision
Procedure/Surgery
Studies have concluded that pterygium surgical excision is the main treatment for pterygium. Pterygium excision with superior graft is the procedure followed most commonly at present. This is achieved by many methods, with the result differing from one method to another. The most important difference is the incidence of recurrence(4)But Varioustechniques such as Bare Sclera, Rotational Conjunctival Flap, Limbal Conjunctival Autograft, Amniotic Membrane Graft, and Free Conjunctival Autograft are also used for the removal of pterygium(3 ,4)Of the various possible alternative approaches, conjunctival autograft is usually preferred. Diverse methods for grafting with sutures, glue or autologous serum from the recipient bed are in use (5,6). Many adjunctive therapies like mitomycin C, corticosteroids, thiotepa, interferon-alpha- 2b, beta irradiation, 5-FU are being used to decrease the risk of recurrence after surgical removal of pterygium.
pterygium excision and conjuctival graft suturing
Procedure/Surgery
pterygium is surgically removed, and a conjuctival graft is placed on bare sclera using sutures to surrounding conjuctiva.
pterygium excision and conjuctival graft placement by autologous blood
Procedure/Surgery
pterygium is surgically removed and a conjuctival graft is placed on bare sclera on which the patient's blood remains. the graft is left without sutures, adhering only by autologous blood.

Treatment groups

70 Participants

are divided into 2 treatment groups

Group A: pterygium excision using sutured techniquePlacebo comparator 2 interventions

Group B: sutureless techniqueActive comparator 2 interventions

Trial outcomes

Primary outcomes

to evaluate the rate of conjuctival graft displacement in pterygium excision and graft placement without sutures

the most valuable aim in this comparative study is to document if the graft placed sutureless will remain in place.So, in each follow-up, graft is assessed in regards to placement.

Time frame

3 months

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Assiut University

Lead sponsor

Source ClinicalTrials.gov

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