Clinical Predictors of Severity in Pediatric Community-Acquired Pneumonia at Assiut University Children's Hospital
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age1-5
SponsorAssiut University
About this trial
This study aims to identify the clinical factors that predict the severity of community-acquired pneumonia (CAP) in pediatric patients. Children admitted to Assiut University Children's Hospital with a diagnosis of CAP will be evaluated through clinical examination, vital signs, laboratory investigations, and radiological findings. The study focuses on determining which clinical features are associated with more severe disease, higher need for oxygen therapy, intensive care admission, or complications. Understanding these predictors may help clinicians recognize severe cases earlier and improve patient management and outcomes.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Children aged 1 month to 5 years.
Children of both sexes
Onset of illness in the community, not more than 48 hours after hospital admission.
Disqualifiers
Children below 1 month, as neonatal pneumonia differs in pathology and management from CAP.
Children with hospital-acquired pneumonia
Known primary or secondary immunodeficiency
Children with chronic respiratory diseases (as cystic fibrosis, bronchiectasis) or congenital lung malformations.
Trial population
Children aged 1 month to 5 years of both sexes diagnosed with community-acquired pneumonia (CAP) presenting to the pediatric emergency department or admitted to pediatric wards at Assiut University Children's Hospital during the study period (October 2025 - October 2026). Children with hospital-acquired pneumonia, known immunodeficiency, chronic respiratory diseases, or congenital lung malformations are excluded.
Trial design
Design model
Other
Time perspective
Prospective
Treatments tested in this trial
Assessment of Pneumonia Severity
Other interventionParticipants undergo structured evaluation for pneumonia severity, including: Clinical predictors (respiratory rate, chest indrawing, hypoxemia, feeding difficulty, mental status, comorbidities) Laboratory markers (complete blood count, RDW, CRP, HCO₃-) Radiological assessment (chest X-ray, CT if indicated) Calculation of RISC score
Treatment groups
67 Participants
are divided into 1 treatment groupGroup A: Children With Community-Acquired Pneumonia1 intervention
Trial outcomes
Primary outcomes
1
Association of Severity Scores with Clinical Outcomes
The primary outcome will be the correlation coefficient (r value) between the Community-Acquired Pneumonia (CAP) severity score and each clinical outcome. The clinical outcomes will include: Length of hospital stay (days) Oxygen requirement (L/min) ICU admission (yes/no) Occurrence of complications (yes/no) Mortality (yes/no)
Time frame
14 days from enrollment (typical hospital stay and outpatient follow-up)2
Severity of Community-Acquired Pneumonia Assessed by the Respiratory Index of Severity in Children (RISC)
CAP severity will be assessed using the Respiratory Index of Severity in Children (RISC) score. The RISC score ranges from 0 to 6, with higher scores indicating more severe disease.
Time frame
4 days from enrollment (typical hospital stay and outpatient follow-up)Locations
Sponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: