About this trial
Hepatectomy is a crucial surgical method for treating liver diseases such as liver cancer, hepatic hemangiomas, and biliary stones. Although hepatectomy has achieved significant therapeutic effects, postoperative complications remain an inevitable issue. Complications following hepatectomy include liver failure, hepatic vascular thrombosis, wound infection at the hepatic incision, and bile leakage, among others. These complications pose a serious threat to patients' health and life, and also increase the waste of medical resources and the cost of treatment. Currently, research on postoperative complications of hepatectomy mainly focuses on small sample studies from a single center, and most studies only focus on a specific complication, lacking comprehensive and systematic analysis. Therefore, it is necessary to conduct a retrospective study analysis of complications related to hepatectomy to more comprehensively and objectively understand the incidence, risk factors, prevention, and treatment of postoperative complications, providing clinical doctors with more scientific treatment plans and guidance.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
1. Patients aged 18-80 years 2.Patients who underwent liver resection surgery at the participating centers
Disqualifiers
Prior cancer treatments such as transarterial chemoembolization, ablation, or targeted therapy.
Repeat liver resection surgeries.
Presence of other malignancies.
Concurrent end-stage diseases including active infections, respiratory failure, decompensated heart failure, and autoimmune disease exacerbations.
Trial population
Patients who underwent liver resection surgery at the participating centers
Trial design
Cohort
Retrospective
Treatments tested in this trial
International Study Group for Liver Surgery (ISGLS)
Diagnostic testAccording to the ISGLS criteria, the patient was judged to have liver failure and further analysis
Treatment groups
Trial outcomes
Primary outcomes
Post-hepatectomy liver failure (PHLF)
PHLF is commonly diagnosed and classified according to the criteria of the International Study Group for Liver Surgery (ISGLS), utilizing markers of liver function measured on or after postoperative day 5 (POD5).
Secondary outcomes
mortality
The patient died postoperatively
Sponsors and contacts
Click on the lead sponsor to view all of their trials.