For patients diagnosed with early gastric cancer involving submucosal invasion, super-ESD indications, or lymph node metastasis, a combination of preoperative endoscopic ultrasound and abdominal contrast-enhanced CT was utilized to ascertain the depth of tumor invasion and to identify any suspicious metastatic lymph nodes in the vicinity of the stomach. Subsequently, a local full-thickness resection, coupled with or followed by individualized precise lymph node dissection, was conducted to fulfill the following objectives: ① To investigate the safety, feasibility, and efficacy of local resection for patients meeting super-ESD criteria; ② To offer a clinical foundation for the individualized and precise lymph node dissection treatment of early gastric cancer.
Age 18-70 years old;
Endoscopic pathological diagnosis: adenocarcinoma;
Enhanced abdominal CT combined with endoscopic ultrasound clinical staging: T1bN0-1M0.
Has not received other treatment;
Pregnant or breastfeeding women
History of previous abdominal surgery
History of other previous malignancies
Can patients with severe heart, lung, brain diseases tolerate surgical treatment
Parallel
Sixty patients with early gastric cancer in stage T1bN0-1M0 were divided into Group A-N0 and Group B-N + according to the presence or absence of lymph node metastasis. When the enrolled patients und
Procedure/SurgeryPatients in group A-No lymph node metastasis, who underwent simple Double-Endoscopic Combined with local full-thickness resection. Patients in group B-imaging examination showed lymph node metastasis. patients were randomly divided into Group N + a and Group N + b. Group N + a: Local full-thickness gastric wall and lymph nodes dissection on D1 or D1 + were performed with Double-Endoscopic Group N + b: Traditional standard surgical gastrectomy and D1 or D1 + lymph nodes dissection was performed .
Rate of recurrence
The operation time, complications and hospital stay were recorded
Click on the lead sponsor to view all of their trials.
This trial is not recruiting at the moment. You can still explore other options:
