About this trial
The goal of this observational study is to explore the clinical influences associated with the development of intestinal barrier dysfunction in patients undergoing gastrointestinal surgery. The main question it aims to answer is:What clinical factors increase the probability of developing intestinal barrier dysfunction in patients after gastrointestinal surgery?
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
men or women aged 18-80 years
expected feasible abdominal surgical treatment (partial gastrectomy, colorectal resection)
no preoperative intestinal barrier dysfunction
patients voluntarily participated in this study and signed an informed consent form.
Disqualifiers
Patients or their families refused to participate in this study
chronic inflammatory diseases (e.g. inflammatory bowel disease, chronic hepatitis, chronic pancreatitis, chronic peptic ulcer, etc.)
history of antibiotic administration in the last 2 weeks
severe cognitive impairment and other inability to cooperate preoperative neoadjuvant radiotherapy
Trial population
People undergoing gastrointestinal surgery
Trial design
Case-control
Prospective
Treatments tested in this trial
No intervention was carried out
Other interventionThis study is an observational study and no intervention was performed on the patients.
Treatment groups
Trial outcomes
Primary outcomes
operating time
Record the patient\'s surgical time
Secondary outcomes
nutritional status
Patients were assessed for risk of malnutrition by the Nutritional Risk Screening Scale (NRS-2002). A score of ≥3 indicated that the patient was at risk of malnutrition.
bowel habit
The patient was asked whether there were increased frequency of stool, changes in stool characteristics, constipation and other conditions before surgery
Surgical Procedures
Record whether the patient underwent laparoscopic surgery or open surgery
hemorrhage
Record the patient\'s intraoperative bleeding volume
Locations
Sponsors and contacts
Click on the lead sponsor to view all of their trials.
This trial is not recruiting at the moment. You can still explore other options: