This study aims to systematically evaluate the therapeutic efficacy of dual-channel endoscopic spinal decompression versus lumbar decompression with fusion for degenerative lumbar spondylolisthesis. Patients undergoing either procedure will undergo detailed preoperative and postoperative follow-up to compare outcomes between the two techniques, specifically assessing postoperative pain relief, neurological improvement, and the incidence of surgical complications.
Aged between 50 and 90 years old with a confirmed diagnosis of degenerative lumbar spondylolisthesis;
Clinical symptoms include chronic pain, nerve compression, or motor dysfunction, confirmed by imaging studies (e.g., MRI or CT);
No significant improvement after at least 3 months of conservative treatment (e.g., medication, physical therapy), meeting surgical indications;
Understand and consent to the relevant procedures of this study, and sign the informed consent form.
Patients exhibiting acute spinal cord compression symptoms or requiring urgent surgical intervention;
Patients with a history of spinal surgery or conditions such as spinal deformities, severe osteoporosis, or active infections that may compromise surgical outcomes;
Patients with severe comorbidities affecting assessment, such as cardiovascular disease, liver or kidney failure, or uncontrolled diabetes;
Patients with psychiatric disorders or cognitive impairments preventing understanding or cooperation with the study process;
Patients with lumbar degenerative spondylolisthesis
Cohort
Prospective
Not listed
VAS
Pain Score
JOA score
Function Score
ODI
Function Score
Click on the lead sponsor to view all of their trials.
