About this trial
The aim of this research is to analyze the effect of a Lactiplantibacillus plantarum Dad-13 supplementation on the gut microbiota profile and performance of adolescent athletes.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Residing in the BPPLOP dormitory of Central Java Province;
Having a normal body mass index;
Being an athlete in an endurance sport;
Having no growth disorders
Disqualifiers
Injury, any health contraindication or failure to perform exercise procedures;
Gastrointestinal infections, diseases, disorders;
Past history of gastrointestinal surgery;
Failure to follow the study protocol;
Trial design
Single group
Treatments tested in this trial
Probiotic Lactiplantibacillus plantarum Dad-13
Dietary supplementLactiplantibacillus plantarum Dad-13 is an indigenous probiotic strain isolated from the curd produced by spontaneous fermentation of buffalo milk in bamboo containers and originates from Minangkabau, West Sumatra, Indonesia.
Treatment groups
Trial outcomes
Primary outcomes
gut microbiota profile
Gut microbiota profiles were measured from fecal samples, then isolated using 16S rDNA sequencing. Fecal samples were collected in the morning. Results: alfa and beta diversity
Short chain fatty acid profile
The total level or amount of short chain fatty acid metabolites produced from the fermentation process in the intestine obtained from feces. Results: Total amount of SCFA, acetic acid, propionic acid, butyric acid
Physical Performance
The physical performance measurement used was VO2max. The VO2max measurement method used a direct laboratory method with COSMED K5 before and after the intervention, with units of kg/mL.
Secondary outcomes
Fecal calprotectin concentration
Protein in white blood cells that acts as an inflammation marker with measurement using ELISA. Fecall samples was used.
Sponsors and contacts
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