Clinical Trial on the Efficacy of Intralesional Triamcinolone Versus Candida Albicans Antigen in Treating Alopecia Areata

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age6+
SponsorUniversidad Autonoma de Nuevo Leon

About this trial

The efficacy of two intralesional treatment modalities for alopecia areata will be determined. Thirty patients over the age of 6 with the diagnosis of alopecia areata on the scalp, with an extension of less than 50%, will be included. A comparison will be made between the effectiveness of intralesional Triamcinolone (standard first-line treatment) and intralesional Candida albicans antigen, with serial clinical and trichoscopic pictures at follow-up to evaluate the clinical response and associated adverse effects.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Diagnosis of alopecia areata

SALT score of less than 50% extension

Has not received any topical or systemic treatment in the last month

Signed informed consent

Disqualifiers

Any skin condition on the scalp (infectious, inflammatory or neoplastic) that could modify the clinical of trichoscopic features

Pregnancy or breast-feeding

Patients in medications that could cause hair loss as side-effects

Trial design

Design model

Parallel

Treatments tested in this trial

  • Candida Albicans Antigen Injection

    Drug

    subcutaneous administration of Candida albicans antigen

Treatment groups

30 Participants
are divided into 2 treatment groups
Group A: intralesional TriamcinoloneActive comparator 1 intervention
Group B: Candida albicans antigenExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Treatment response

porcentage of hair growth determined by SALT score

Time frame
5 months

Secondary outcomes

1

Side effects

Side effects associated to the treatment

Time frame
5 months

Other outcomes

Sponsors and contacts

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