Clinical Usefulness of Virtual Ablation Guided Catheter Ablation of Atrial Fibrillation: Virtual Rotor Mapping and Catheter Ablation

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age19-80
SponsorYonsei University

About this trial

Radiofrequency catheter ablation is effective in the treatment of patients with paroxysmal atrial fibrillation. In order to reduce the recurrence rate after catheter ablation, the investigators propose to apply 'virtual' ablation on patient-specific atria by simulating 3D atrial computer model. The investigators will conduct virtual rotor mapping in the patient specific atrial model. Then, the investigators will compare the clinical outcome of conventional circumferential pulmonary vein isolation and additional rotor ablation guided by virtual rotor mapping.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

AF patient age 19~80

Diagnosis of AF patients who performed catheter ablation of atrial fibrillation due to uncontrolled pulse rate by anti-arrhythmic drug therapy.

Disqualifiers

AF patients who have severe heart deformations or vascular disease.

The patient who have renal disease of eGFR<30mL/min

The patients who had been performed catheter ablation of atrial ablation and MAZE.

The patients who missed out to recording of 3D CT, echo and electrocardiography.

Trial design

Design model

Parallel

Treatments tested in this trial

  • physician's personal experience

    Procedure/Surgery

    physician's personal experience

  • Virtual rotor mapping

    Procedure/Surgery

    Virtual rotor mapping

Treatment groups

110 Participants
are divided into 2 treatment groups
Group A: conventional groupActive comparator 1 intervention
Group B: 3D atrial computer modelExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Recurrence rate of atrial fibrillation of 18 months after procedure within 18 months

Time frame
18 months
2

Rate of mortality, incidence of cerebral infarction and hospitalization after procedure

Time frame
24 months

Secondary outcomes

1

Major complication related procedure : Complication of hemorrhagic and embolic

Time frame
24 months
2

Pericardial effusion required treatment, 4g/dL reduced level of Hb, Hemorrhage required blood transfusion and Cerebral infarction related procedure

Time frame
24 months
3

Procedure time and Radiofrequency ablation time

Time frame
24 months

Other outcomes

Sponsors and contacts

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