About this trial
Patients undergoing extracorporeal membrane oxygenation (ECMO) are at increased risk of wound complications at the vascular access site after decannulation. These complications may delay recovery and increase healthcare burden. Closed incision negative pressure wound therapy (NPWT) may improve wound healing by reducing fluid accumulation and supporting the incision. This study evaluates whether prophylactic NPWT reduces wound complications compared to standard wound care following ECMO decannulation.
Eligibility criteria
Qualifiers
Patient is aged 18 years or older
Is currently receiving ECMO therapy and is eligible for weaning from the device
The patient must have at least one cannula inserted at the groin site
(Proxy) informed consent
Disqualifiers
Duration ECMO run < 24 hours
Expected death within 24 hours after decannulation
Extracorporeal carbon dioxide removal (ECCO2R) using low blood flow devices or pumpless devices (i.e., MINILUNG ®, PrismaLung+)
Wound closure is not possible after decannulation.
Trial design
Treatments tested in this trial
- Prophylactic Closed-Incision Negative Pressure Wound Therapy
- Standard Wound Dressing
Treatment groups
Locations
Sponsors and collaborators
St. Antonius Hospital
Lead sponsor
St. Antonius Onderzoeksfonds
Collaborator
St. Antonius innovatiefonds
Collaborator