Closed Incision NPWT to Prevent Wound Complications Post-ECMO

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorSt. Antonius Hospital

About this trial

Patients undergoing extracorporeal membrane oxygenation (ECMO) are at increased risk of wound complications at the vascular access site after decannulation. These complications may delay recovery and increase healthcare burden. Closed incision negative pressure wound therapy (NPWT) may improve wound healing by reducing fluid accumulation and supporting the incision. This study evaluates whether prophylactic NPWT reduces wound complications compared to standard wound care following ECMO decannulation.

Eligibility criteria

Qualifiers

Patient is aged 18 years or older

Is currently receiving ECMO therapy and is eligible for weaning from the device

The patient must have at least one cannula inserted at the groin site

(Proxy) informed consent

Disqualifiers

Duration ECMO run < 24 hours

Expected death within 24 hours after decannulation

Extracorporeal carbon dioxide removal (ECCO2R) using low blood flow devices or pumpless devices (i.e., MINILUNG ®, PrismaLung+)

Wound closure is not possible after decannulation.

Trial design

Treatments tested in this trial

  • Prophylactic Closed-Incision Negative Pressure Wound Therapy
  • Standard Wound Dressing

Treatment groups

144 Participants
are divided into 2 treatment groups

Locations

This trial has no locations

Sponsors and collaborators

St. Antonius Hospital

Lead sponsor

St. Antonius Onderzoeksfonds

Collaborator

St. Antonius innovatiefonds

Collaborator