Cochlear Implant Speech in Noise Processing
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-99
SponsorCraig D. Workman, PhD
About this trial
The study will help us in understanding the neural mechanisms by which listeners with a cochlear implant detect speech in noisy environments.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Between 18 and 99 years of age.
Have a cochlear implant activated for more than one year.
Eligible for research under the Iowa Cochlear Implant Project VIII.
Ability to understand and willingness to sign a written informed consent document.
Disqualifiers
Medical history includes seizure disorder, head injury, neurologic, metabolic, cardiovascular disease, or previous cerebrovascular event (unless approved by PI).
Female self-reporting pregnancy. A urine pregnancy test will be performed prior to injection of the radiopharmaceutical.
Currently taking medications which may affect cerebral blood flow (e.g., papaverine, ginkgo biloba, acetazolamide).
Uncontrolled intercurrent illness that would limit compliance with study requirements per investigator.
Trial design
Design model
Parallel
Treatments tested in this trial
Cochlear implant
DeviceCochlear implant
Treatment groups
150 Participants
are divided into 2 treatment groupsGroup A: Cochlear implantExperimental treatment 1 intervention
Group B: Age-typical hearing controlNo intervention 0 interventions
Trial outcomes
Primary outcomes
1
To identify the cortical bases for speech-in-noise understanding in cochlear implant users
PET imaging will be used to identify the brain regions for listeners ability to recognize speech in noise at different signal-to-noise ratios.
Time frame
Basline VisitSponsors and contacts
Click on the lead sponsor to view all of their trials.
Craig D. Workman, PhD
Lead sponsor
University of Iowa
Sponsor institution
Source ClinicalTrials.gov