Coexistence of Cerebral and Coronary Atherosclerosis in Acute Ischemic Cerebrovascular Disease Patients Registry (CoCCA) is a single-center observational registry of patients hospitalized for acute ischemic cerebrovascular disease (AICVD) with atherosclerotic changes in both cerebral and coronary arteries.
This registry aims to establish quantified risk stratification and prognostic models, as well as suggest effective diagnostic and therapeutic strategies.
Diagnosed as ischemic stroke or transient ischemic attack (TIA).
Less than 30 days after onset of ischemic stroke or TIA symptoms.
Extracranial or intracranial cerebral atherosclerosis confirmed by vascular ultrasound or CT angiograpgy or MR angiograpgy or digital substraction angiography.
Coronary atherosclerosis confirmed by CT angiograpgy or MR angiograpgy or digital substraction angiography; or with myocardial ischemia symptoms confirmed using electrocardiogram or echocardiography or cardiac MR; or with a history of percutaneous coronary intervention or coronary artery bypass graft.
With malignant tumors or poor organ functions or hematologic diseases, whose estimated life expectancy is less than 5 years.
Patients refuse to participate in the research.
acute ischemic cerebrovascular disease patients with coexistence of cerebral and coronary atherosclerosis
Cohort
Prospective
observational only- no intervention
Other interventionobservational only- no intervention
Rate of Major Adverse Cardiovascular Events
cardiovascular mortality (any mortality due to ischemic stroke, myocardial infarction, other cardiac diseases, or unobserved sudden death), ischemic stroke, myocardial infarction and unstable angina
Rate of Major Adverse Cardiovascular Events
cardiovascular mortality (any mortality due to ischemic stroke, myocardial infarction, other cardiac diseases, or unobserved sudden death), ischemic stroke, myocardial infarction and unstable angina
Functional Outcome
Percentage of patients with modified Rankin Scale (mRS) scores (minimum 0 and maximum 5) 3 to 5, who are considered to be disabled.
Rate of Ischemic Stroke
fatal and nonfatal ischemic stroke.
Rate of Acute Coronary Syndrome
fatal and nonfatal myocardial infarction and unstable angina
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