Cognitive Enhancement in Unipolar Depression With Yoga
ConditionUnipolar Depression
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-60
SponsorUniversity of Pittsburgh
About this trial
It is evident from recent studies that cognitive deficits persist even after remission of depressive episode. Hence, in this study, the investigators would like to see whether specific Yoga practice will help in enhancing cognitive abilities in this population.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age more than 18years and less than 60 years
H/o at least one depressive episode which is under remission and at the time of examination and throughout the study duration,
Informed Consent
Disqualifiers
Comorbid Psychosis, OCD, Bipolar disorder
Comorbid ADHD, IDD
Comorbid substance dependence (except tobacco)
Comorbid major or minor cognitive impairment,
Trial design
Design model
Parallel
Treatments tested in this trial
Adjuvant yoga intervention
BehavioralThe yoga will include following asanas under the supervision of a yoga therapist. This will include Griva Shithilikarana, Skandha Sanchalana , Kati Sanchalana, Jaanu Sanchalana, Pada Sanchalana, Tadasana, Kati Sakti Vikasaka, Konasana,Marjari Asana, Vakrasana, Pascimottanasana, Matsyasana, Bhujangasana, Ardha Shalabhasana, Viparitakarani, Pavanamuktasana, Setubhandasana, Shavasana, Kapalabhati, Surya-anuloma pranayama, Chandraanuloma pranayama, Bhastrika, Bhramari Pranayama, Nadanusandhana.
Treatment groups
32 Participants
are divided into 2 treatment groupsGroup A: Adjuvant yoga intervention groupExperimental treatment 1 intervention
Group B: Treatment as usual groupNo intervention 0 interventions
Trial outcomes
Primary outcomes
1
Working memory (Digit Span)
To study the change in working memory in intervention group as measured by digit span test in comparison to treatment as usual. The range of the scale is 0 to 28 points and higher is better memory.
Time frame
Baseline, after six weeks yoga and after four weeks of completion of yoga2
Attention and processing speed(Trail A and B)
To study the change in attention and processing speed in intervention group as measured by Trail A and B test in comparison to treatment as usual. The scoring is based on time taken to complete the test. Less the time taken, better the attention and processing speed.
Time frame
Baseline, after six weeks yoga and after four weeks of completion of yoga3
Cognitive flexibility
To study the change in cognitive flexibility in intervention group as measured by stroop test test in comparison to treatment as usual. Stroop test also measures time to complete the task and less the time, better the score is.
Time frame
Baseline,after six weeks yoga and after four weeks of completion of yoga4
Cognitive inhibition
To study the change in cognitive inhibition in intervention group as measured by stroop test test in comparison to treatment as usual.
Time frame
Baseline,after six weeks yoga and after four weeks of completion of yogaSecondary outcomes
1
Sustainability of working memory
To compare the difference in the working memory 4 weeks post adjuvant yoga intervention, as measured by the scores on Digit span test.test in comparison to treatment as usual.The range of the scale is 0 to 28 points and higher is better memory.
Time frame
four weeks of completion of yoga2
Sustainability of attention and processing speed
To compare the difference in attention and processing speed 4 weeks post adjuvant yoga intervention, as measured by Trail Making A and B tests. The scoring is based on time taken to complete the task. Less the time taken, more is the attention and processing speed.
Time frame
four weeks of completion of yoga3
Sustainability of cognitive flexibility
To compare the difference incognitive flexibility 4 weeks post adjuvant yoga intervention, as measured by Stroop test. Stroop test also measures time to complete the task and less the time, better the cognitive flexibility is.
Time frame
four weeks of completion of yoga4
Sustainability of cognitive inhibition
To compare the difference in cognitive inhibition weeks post adjuvant yoga intervention, as measured by the scores on Stroop test.
Time frame
four weeks of completion of yogaSponsors and contacts
Click on the lead sponsor to view all of their trials.
University of Pittsburgh
Lead sponsor
Fogarty International Center of the National Institute of Health
Collaborator
National Institute of Mental Health and Neuro Sciences, India
Collaborator
Source ClinicalTrials.gov