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Cognitive Impairment in Older Adults With Hematologic Malignancies

ConditionsCognitive ImpairmentHematologic MalignanciesChemotherapy Effect
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age65+
SponsorAssiut University

About this trial

This cross-sectional study aims to determine the prevalence of cognitive impairment and evaluate its relationship with activities of daily living among older adults with hematologic malignancies receiving chemotherapy.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

- Age 65 years or older

Confirmed diagnosis of hematologic malignancy

Currently receiving chemotherapy

Able to communicate and participate in cognitive assessment

Disqualifiers

- Previously diagnosed dementia before the diagnosis of malignancy

Delirium at the time of assessment

Severe visual or hearing impairment interfering with cognitive testing

History of major neurological disorders affecting cognition

Trial population

Older adults aged 65 years or older with confirmed hematologic malignancies receiving chemotherapy at Assiut University Hospitals.

Trial design

Design model

Case-only

Time perspective

Cross-sectional

Treatments tested in this trial

Not listed

Trial groups

120 Participants
are grouped into 1 trial group
Group A: Single cohort: Older adults with hematologic malignancies

Trial outcomes

Primary outcomes

1

Prevalence of cognitive impairment

Proportion of participants with cognitive impairment defined as a Montreal Cognitive Assessment (MoCA) score less than 26.

Time frame
Baseline

Secondary outcomes

1

Mean MoCA score

Mean Montreal Cognitive Assessment (MoCA) score (range 0-30, higher scores indicate better cognition)..

Time frame
Baseline
2

Mean Katz ADL score

Mean Katz Index of Independence in Activities of Daily Living score (range 0-6, higher scores indicate greater independence).

Time frame
Baseline
3

Mean Lawton IADL score

Mean Lawton Instrumental Activities of Daily Living score (range 0-8, higher scores indicate greater independence)

Time frame
Baseline
4

Proportion with impaired activities of daily living

Proportion of participants with impaired Katz ADL score.

Time frame
Baseline

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Assiut University

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: