Cognitive Processing Therapy for Posttraumatic Stress Disorder and Co-occurring Lived Experience Stress

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorBoston University

About this trial

Populations facing health disparities include groups with significantly higher rates of posttraumatic stress disorder than the general population who frequently experience lived experience stress, which may complicate posttraumatic stress disorder symptom presentations. However, there are currently no posttraumatic stress disorder treatments designed to meet the unique needs of these individuals.

The proposed study will pilot an adaptation of Cognitive Processing Therapy (a gold-standard treatment for posttraumatic stress disorder) that has been modified to incorporate the impact of lived experience stress as an additional treatment target. This project has the potential to advance our understanding of how to enhance Cognitive Processing Therapy in order to optimize posttraumatic stress disorder treatment response and mitigate health disparities.

Eligibility criteria

Qualifiers

Current diagnosis of PTSD

Self-identification as a sexual or gender minority (SGM) individual

Endorsement of SGM stress experiences with moderate distress

For patients who take psychiatric medication, stable dose one month prior to enrollment

Disqualifiers

Current active suicidal or homicidal ideation with intent or plan

Unstable bipolar disorder/current mania

Unstable psychotic disorder/current psychosis

Current severe substance use that warrants immediate medical attention

Trial design

Treatments tested in this trial

  • Standard CPT
  • CPT-LEAP

Treatment groups

52 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Boston University

Lead sponsor

National Institute of Mental Health (NIMH)

Collaborator