Despite international efforts to identify biomarkers of depression, none has been transferred to clinical practice, neither for diagnosis, evolution, nor therapeutic response. This led us to build a French national cohort (through the clinical and research network named SoPsy within the French biological psychiatry society (AFPBN) and sleep society (SFRMS)), to better identify markers of sleep and biological rhythms and validate more homogeneous subgroups of patients, but also to specify the manifestations and pathogeneses of depressive disorders.
Individuals with depressive episode characterized according to the DSM-5 criteria regardless of the associated characteristics and comorbidities.
Adult and child
Affiliated to a social security
don't understand or read french
Medical condition incompatible with administration of questionnaire
impossibility to give informed decision (subject in an emergency condition, etc.)
The entry point for the cohort is any patient with a major depressive episode, in order to integrate the maximum variance in terms of manifestations, and thus to be able to contrast the different clinical pictures according to the biomarkers of sleep and biological rhythms. The aim of this cohort is to pool the efforts of this network and to homogenise the assessments, in order to characterise more precisely and in a standardised manner the alterations in sleep and rhythms in depressive disorders, according to the different subtypes of disorder.
Cohort
Prospective
Not listed
amount of REM sleep
during the polysomnography, amount of REM sleep (in minutes)
duration of the first stage of REM sleep
duration of the first episode of N3
latency of the first episode of N3
duration of N1 slow-wave sleep
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