About this trial
This retrospective cohort study (Hong Kong PECT Registry) compares treatment outcomes between different percutaneous catheter-based therapies in patients with acute pulmonary embolism (PE). PE is a critical condition with potential for rapid deterioration and mortality before treatment. While availability of catheter-based therapy contributed to the declining mortality rates of PE, selecting the appropriate intervention remains key. There are primarily two modes of therapies available: Catheter-directed thrombolysis and Aspiration thrombectomy (e.g., Penumbra, Flowtriever, AlphaVac) Given limited direct comparisons between these methods, the study will evaluate their efficacy, safety, and clinical outcomes of these treatment strategies in acute PE patients.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patients who is admitted with a diagnosis of acute pulmonary embolism
Patient who receives any types of catheter-based therapy for acute pulmonary embolism.
Disqualifiers
nil. This is a all-comer registry.
Trial population
This registry aims to evaluate the efficacy and safety of patients with acute PE treated with catheter-based therapy.
Trial design
Cohort
Prospective
Treatments tested in this trial
catheter-based therapy
Devicecatheter-based therapy
Treatment groups
Trial outcomes
Primary outcomes
Inpatient mortality rates
death of a patient occurring during the index hospitalization of pulmonary embolism.
Secondary outcomes
procedural related complications
safety outcomes
major bleeding (as defined by BARC)
safety outcomes
hemoglobin change within 72 hours of the procedure
safety outcomes
change in the right ventricle to left ventricle ratio
procedural efficacy
Other outcomes
90 days overall mortality rate
90 days mortality rate
PE recurrence by 90 days
recurrence of PE by 90 days
Sponsors and contacts
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Chinese University of Hong Kong
Lead sponsor
China Medical University, Taiwan
Collaborator